Ursodeoxycholic acid 128-13-2 Tsarin narkewar abinci Cholagogic
Biya:T/T, L/C
Asalin samfur:China
Tashar Jirgin Ruwa:Beijing/Shanghai/Hangzhou
Ƙarfin samarwa:2000kg/wata
Oda (MOQ):25kg
Lokacin Jagora:3 Ranakun Aiki
Yanayin ajiya:Ajiye a wuri mai sanyi, busasshiyar wuri, zazzabin ɗaki.
Kunshin kayan:ganga
Girman kunshin:25kg/ganga
Bayanin aminci:Ba kayan haɗari ba
Gabatarwa
Ursodeoxycholic acid (UDCA), wanda kuma aka sani da ursodiol, wani bile acid ne na biyu, wanda aka samar a cikin mutane da yawancin sauran nau'in daga metabolism ta kwayoyin hanji.An haɗe shi a cikin hanta a wasu nau'ikan, kuma an fara gano shi a cikin bile na bear, wanda shine asalin sunan ta Ursus.A cikin tsaftataccen tsari, an yi amfani da shi don magance ko hana cututtuka da yawa na hanta ko bile ducts.
An yi amfani da UDCA azaman magani na likita a cikin cututtukan gallstone (cholelithiasis) da kuma sludge biliary.UDCA yana taimakawa rage yawan ƙwayar cholesterol na bile kuma yana haifar da rushewar gallstones masu wadatar cholesterol a hankali.
Ana iya ba da UDCA bayan tiyata na bariatric don hana cholelithiasis, wanda yawanci ke faruwa saboda saurin asarar nauyi wanda ke haifar da biliary cholesterol oversaturation da kuma biliary dyskinesia na biyu na hormonal canje-canje.
Ƙayyadaddun bayanai (EP10)
| Abu | Ƙayyadaddun bayanai |
| Bayyanar | Fari ko kusan fari foda |
| Solubility | A zahiri wanda ba a iya narkewa a cikin ruwa, mai narkewa cikin yardar kaina a cikin ethanol (96%), mai narkewa a cikin acetone, kusan ba zai iya narkewa cikin methylene chloride |
| Wurin narkewa | 202-204 ℃ |
| Ganewa | Bakan IR iri ɗaya kamar ursodeoxycholic acid CRS |
| Babban tabo a cikin chromatogram da aka samu tare da maganin gwajin (b) yana kama da matsayi, launi da girma zuwa wurin ka'ida a cikin chromatogram da aka samu tare da bayani na tunani (a). | |
| Dakatar da aka samu shine kore-shuɗi. | |
| Takamaiman jujjuyawar gani | + 58.0 ~ + 62.0 ° |
| Rashin tsarki C | Lithocholic acid ≤ 0.1% |
| Abubuwan da ke da alaƙa (HPLC) | rashin tsarki A: chenodeoxycholic acid ≤ 1.0% |
| ƙazantar da ba a bayyana ba ≤ 0.1% | |
| jimlar ≤ 1.5% | |
| Karfe masu nauyi | ICH Q3D |
| Asarar bushewa | ≤ 1.0% |
| Sulfate ash | 0.1% |
| Assay | 99.0% ~ 101% (bushewar abu) |
| Ragowar kaushi | Acetone ≤ 5000 ppm Ethyl acetate ≤ 5000 ppm Isopropanol ≤ 5000 ppm Ethanol ≤ 5000 ppm |
| Gwajin Kwayoyin Halitta | Jimlar ƙididdiga ƙananan ƙwayoyin cuta na aerobic ≤ 10³CFU/g Jimlar yisti da ƙuraje suna ƙidaya ≤ 10²CFU/g Escherichia coli: Babu a cikin 1 g Salmonella: Babu a cikin 10 g |
| Ƙarin kaddarorin | |
| Rarraba girman barbashi | 100% lambar wucewa 180 sieve (100% wuce 80 raga sieve) |
