Amphotericin B 1397-89-3 Kwayoyin cuta
Biya:T/T, L/C
Asalin samfur:China
Tashar Jirgin Ruwa:Beijing/Shanghai/Hangzhou
Ƙarfin samarwa:100kg/wata
Oda (MOQ):25kg
Lokacin Jagora:3 Ranakun Aiki
Yanayin ajiya:tare da jakar kankara don sufuri.Ajiye a 2-8 ℃ na dogon lokaci.
Kunshin kayan:ganga
Girman kunshin:25kg/drum
Bayanin aminci:Ba kayan haɗari ba
Gabatarwa
Amphotericin B, ana iya kiransa da Fungizone ko Ambisome, wanda shine maganin rigakafi na polyene wanda aka ware daga matsakaicin al'ada na Streptomycesnodosus.An keɓe shi da kashi biyu tare da A da B, amma A part ba shi da ƙarancin aiki don maganin fungal wanda ba a amfani da shi, don haka mutane suna amfani da sashin B kawai wanda ake kira Amphotericin B.
Magani ne na maganin fungal da ake amfani da shi don cututtukan fungal masu tsanani da leishmaniasis.Yana da amfani guda biyu daban-daban ta baka da allura.
Amphotericin B shine zabi na farko don kamuwa da cututtukan fungal mai zurfi saboda girman bakan maganin fungal.Yana da hana aiki ga fungals kamar cryptococcus, coccidium, candida albicans da blastomycetes, da dai sauransu. Za su kashe fugal a babban taro, wanda shi ne m magani ga lura da zurfin fungal kamuwa da cuta.
Babban alamun asibiti kamar: 1. Maganin fungal irin su cryptococcosis, blastomycosis na Arewacin Amurka, candidiasis da aka yada, coccidiosis da histoplasmosis.2. Maganin mucormycosis da wasu fungals kamar Rhizopus, colporium, endomycetes da frog fecal mold ke haifarwa.3. Maganin sporotrichosis wanda sporotrichosis schenckii ya haifar.4. Maganin aspergillosis wanda Aspergillus fumigatus ya haifar.5. Topical shirye-shirye dace da pigmented mycosis.Hakanan ya dace da kamuwa da cututtukan fungal na fata bayan konewa, ƙwayar numfashi Candida da Aspergillus ko kamuwa da cuta na cryptococcus, da kuma aiki don cututtukan fungal na corneal.
Abubuwan da ke faruwa na yau da kullun sun haɗa da zazzaɓi, sanyi, da ciwon kai jim kaɗan bayan an ba da maganin, da kuma matsalolin koda.Alamun rashin lafiyar ciki har da anaphylaxis na iya faruwa.Sauran munanan illolin sun haɗa da ƙarancin potassium na jini da kumburin zuciya.Ya bayyana yana da lafiya a cikin ciki.Akwai nau'in lipid wanda ke da ƙananan haɗarin sakamako masu illa.Yana cikin nau'in magunguna na polyene kuma yana aiki a wani ɓangare ta hanyar tsoma baki tare da kwayar cutar tantanin halitta na naman gwari.Dole ne a yi amfani da hankali lokacin da yanayi ya faru, don amfani da aminci dole ne ya bi shawarar ma'aikatan lafiya.
Ƙididdiga Matsayin Baka (A cikin Matsayin Gida)
| Abu | Ƙayyadaddun bayanai |
| Bayyanar | Yellow zuwa orange-yellow foda, mara wari ko kusan mara wari. |
| Ganewa | IR, HPLC |
| pH | 4.0-6.0 |
| Asara akan bushewa | ≤5.0% |
| Sulfated ash | ≤3.0% |
| Abubuwa masu alaƙa | ≤0.5% |
| 303nm ku | Najasa A (Amphotericin A) ≤5.0% Najasa wanda ba a san shi ba ≤1.0% |
| 383nm ku | Najasa B (Amphotericin X1) ≤4.0% Najasa wanda ba a san shi ba ≤2.0% |
| Jimlar ƙazanta | ≤15.0% |
| Ragowar kaushi | Methanol ≤0.3% Acetone ≤0.5% |
| Assay | ≥850 amphotericin B raka'a/mg don busasshen abu. |
Ƙididdiga Matsayin Baka (A cikin Matsayin Gida)
| Abu | Ƙayyadaddun bayanai |
| Bayyanar | Yellow zuwa orange foda. |
| Ganewa | IR, HPLC |
| Ragowa akan kunnawa | ≤0.5% |
| Abubuwan da ke da alaƙa |
|
| ku 303nm | Amphotericin A ≤2.0% |
| Najasa wanda ba a san shi ba ≤1.0% | |
| ku 383nm | Amphotericin X1 ≤4.0% |
| Najasa wanda ba a san shi ba ≤2.0% | |
| Jimlar ƙazanta | ≤15.0% |
| Ragowar kaushi | Acetone ≤0.5% |
| Methanol ≤0.3% | |
| Iyakar microbiological | Ƙididdigar ƙananan ƙwayoyin cuta na Aerobic ≤1000cfu/g |
| Molds & yisti ≤100cfu/g | |
| Escherichia coli Ba ya cikin 1g | |
| Bacterial endotoxins | <1.0EU/mg |
| Assay | ≥850 amphotericin B raka'a/mg, lissafta akan busasshen tushe |
