Samfura

Afoxolaner tsari nemaganin kashe kwarikumaacaricidewanda ake gudanarwa ta baki ko a sama.

Afoxolaner yana hanaAminobutyric acid(GABA) -gated chloride tashoshi (GABAA receptors) da L-glutamate-gated chloride tashoshi (GluCls).Ƙarfin Afoxolaner yana kama dafipronil.

Yana da wani nau'in kwari mai yadu tare da kyakkyawan aikin kwari akan ticks, fleas, lice, hemiptera da diptera, kuma cutarwarsa ya fi ko kwatankwacinsa na maganin kwari da aka saba amfani da shi.

A asibiti yana nuna cewa Afoxolaner na iya ba da kariya ta tsawon mako 12 ga karnuka zuwa tasirin ectoparasite na rigakafi.Ya fi sauƙi da inganci ga duka dabbobin gida da kuma masaukin dabbobi.

Yana iya fitar da kashe ƙuma ga karnuka.Yana iya ɗaukar tasiri da sauri akan ƙwanƙarar manya kuma yana daɗe na dogon lokaci.Hakanan zai iya hana ƙudawa shiga cikin ƙwai, don haka lalata yanayin rayuwar ƙuma.Wadannan ectoparasites na dabbobi na yau da kullun suna shan abinci mai gina jiki na dabbobi, kuma suna iya yada cututtuka da yawa, kamar tsutsotsi masu ƙonewa, cutar Lyme, ciwon daji na daji, da dai sauransu. Ba wai kawai zai shafi ci gaba da lafiyar dabbobin gida ba, har ma yana haifar da haɗarin lafiya ga masu mallakar dabbobi.Afoxolaner ba shi da wani aiki akan masu karɓar tsarin juyayi na mammalian, don haka yana da aminci ga dabbobi masu shayarwa.

Afoxolaner kusan bazuwar kananan dabbobi.Asalin nau'in kwayoyin halitta a kusa da 90-100% ana fitar dashi ta hanyar najasa ba tare da metabolites ba.Kusan babu excretion na koda, kyakkyawan aminci, babu lahani ga hanta da koda na kananan dabbobi.

Ba shi da sanannen juriya na miyagun ƙwayoyi da haramtattun daidaiton ƙwayoyi, kuma baya juriya ga magungunan kwari da ke akwai.Bayan gudanar da baki, ana rarraba maganin a ko'ina a jikin jiki.Yana aiki awanni 2 bayan gudanar da baki.Bayan sa'o'i 4, zai iya kashe akalla 80% na kwari.Lokacin kariyar na iya kaiwa makonni 12.Maimaita kamuwa da cuta kuma na iya samun sakamako mai kyau na maganin kwari.Wani nau'i ne na maganin ectoparasite na antibody tare da babban aminci, wanda ya cancanci amfani da shi.